Table 4

Multi-gene editing in farm animals

Species Gene Modification Approach Reference
Pig CD163 and APN Knock-out CRISPR/Cas9 [109]
Pig CD163, MSTN, and IGF2 Mutation Cytodine base editor [110]
Goat MSTN and FGF5 Knock-out CRISPR/Cas9 [111]
Sheep MSTN, ASIP, and BCO2 Knock-out CRISPR/Cas9 [112]

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