Figure 3

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(a) TEM image of HA@COF NSs (Scale bar: 10 μm). (b) AFM image of HA@COF NSs with its height curve in (c). (d) flow cytometry analysis of the apoptosis of 4T1 cells with various operations. Reproduced with permission from Ref. [97], Copyright 2021, THE SOCIETY. (e) DLS analysis for 2D COF NSs. (f) Adjusted tumor size over a 2-week treatment period. (g) Schematic diagram of the synthesis of the CApHD NSs. (h) Tracing ROS generation with fluorescence detection of DCFH under various irradiation time (0.625 W cm−2). (i) Photothermal detection of two COF NSs (without and with Au) by 635 nm laser. (j) Dox release rate varies under various circumstances. Reproduced with permission from Ref. [98], Copyright 2021, THE SOCIETY.

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