(a) The schematic structures of COF-1 to COF-9. (b) Porosity analysis by low-temperature (77 K) N₂ sorption analysis and (c) Morphological analysis by FE-SEM in a scale bar of 200 nm of COF-3. (d) Cell viability decreases considerably with increasing concentrations of PTX alone and in combination with COF-3. Reproduced with permission from Ref. [100], Copyright 2024, American Chemical Society. (e) Dox release of TpDh-DT under various conditions. (f) Cell viability test of MCF-10A and MCF-7 cells treated with three COFs. (g) Schematic drawing of TpDh-DT relating to fabrication, tumor cell imaging, and cancer treatment. Reproduced with permission from Ref. [86], Copyright 2021, American Chemical Society.