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Table 3

Comparison of representative inference framework for MLLMs deploymenta)

Framework Core optimization Key MLLM support Multi-modal Primary use case Target platforms
vLLM [158] PagedAttention, throughput HF Hub seamless integration High-throughput batch processing / Stateless APIs NV, AMD, TPU, AWS
SGLang [159] RadixAttention, graph opt Llama, DeepSeek, LLaVA Latent-sensitive chat / Complex agentic systems NV, AMD GPUs
llama.cpp [160] GGUF quantization, lightweight kernels LLaMA series, Falcon, Qwen2-VL, LLaVA CPU-heavy inference / local prototyping Apple, ARM, x86, NV, Mobile GPU
TensorRT-LLM [161] Deep operator fusion, speculative decoding GPT, MoE, quantized LLMs Industrial-grade production on NVIDIA clusters NV GPUs, Clusters
MLC-LLM [162] TVM compiler-based, universal deployment Llama, Mistral, GPT-2, Phi-3.5, Qwen3 Universal cross-platform “write-once-run-anywhere" iOS, Android, ARM, NV/AMD/Intel
MNN [163] Heterogeneous computing, mobile-specific kernels Qwen, Yi, InternLM, SmolM, MiMo Ultra-resource-constrained mobile NPU/GPU tasks Mobile NPU/GPU, Vulkan, Metal

a) NV: NVIDIA; HF Hub: Hugging Face Model Hub; GGUF: GPT-Generated Unified Format; TVM: Tensor Virtual Machine; NPU: Neural Processing Unit; AWS: Amazon Web Services; TPU: Tensor Processing Unit.

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